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Description:However, AI therapy is known to induce bone loss leading to osteoporosis with an increased risk for fragility fractures. The purpose of this study was to investigate whether changes of magnetic resonance MR -based trabecular bone microstructure parameters as advanced imaging biomarker can already be detected in subjects with AI intake but still without evidence for osteoporosis according to dual energy X-ray absorptiometry DXA -based bone mineral density BMD measurements as current clinical gold standard. All subjects underwent 3 Tesla magnetic resonance imaging MRI of the distal radius to assess the trabecular bone microstructure.
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